ERA is a digital repository of original research produced at The University of Edinburgh. The archive contains documents written by, or affiliated with, academic authors, or units, based at Edinburgh that have sufficient quality to be collected and preserved by the Library, but which are not controlled by commercial publishers. Holdings include full-text digital doctoral theses, masters dissertations, project reports, briefing papers and out-of-print materials.
Information on current research activity including staff, projects and publications is available via the Edinburgh Research Explorer.
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Role of the nuclear basket in regulating the senescence-associated secretory phenotype
(The University of Edinburgh, 2024-05-17)Oncogene-induced senescence is a state of irreversible cell cycle arrest, accompanied by the secretion of signalling molecules, including pro-inflammatory cytokines and chemokines. These are collectively known as the ... -
Identifying mistranslating mRNAs in mouse models of autism
(The University of Edinburgh, 2024-05-17)Autism Spectrum Disorders (ASD) define a range of debilitating early-onset and life-long conditions affecting neurodevelopment and brain functionality. Many autism risk genes are negative regulators of synaptic protein ... -
Development of attachment in infants born preterm
(The University of Edinburgh, 2024-05-17)Preterm birth (birth before 37 weeks of gestation) is associated with atypical neurodevelopmental outcomes in childhood, including socioemotional difficulties and attention problems. Positive infant attachment relationships ... -
Morphological and molecular basis of human ectodermal appendage formation
(The University of Edinburgh, 2024-05-17)The presence of hair is a key trait of mammals. Hair follicles develop in the skin, with early follicles composed of an epidermal placode and a dermal condensate. Most experimental studies of hair follicle development have ... -
Investigating the motor neuron translatome in spinal muscular atrophy and normal postnatal development
(The University of Edinburgh, 2024-05-17)Translation is a process that involves the protein production through ribosomal interaction with the messenger ribonucleic acid (mRNA). This process has been shown to be affected in multiple neurodegenerative diseases ...